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Characterizing CD38 Expression and Enzymatic Activity in the Brain of Spontaneously Hypertensive Stroke-Prone Rats

Background: CD38 is a transmembrane glycoprotein that catabolizes nicotinamide adenine dinucleotide (NAD(+)) and is the main source for the age-dependent decrease in NAD(+) levels. Increased CD38 enzymatic activity has been implicated in several neurological diseases. However, its role in the pathog...

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Detalles Bibliográficos
Autores principales: Hannawi, Yousef, Ewees, Mohamed G., Moore, Jordan T., Zweier, Jay L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194821/
https://www.ncbi.nlm.nih.gov/pubmed/35712720
http://dx.doi.org/10.3389/fphar.2022.881708