Response to Pralsetinib Observed in Meningeal-Metastatic EGFR-Mutant NSCLC With Acquired RET Fusion: A Brief Report

INTRODUCTION: RET is well known as an important driver gene in NSCLC. Moreover, RET is a rare acquired resistance mechanism to EGFR-mutant NSCLC. Only 36 NSCLC cases of coexistence of EGFR and RET were reported previously worldwide. So far, there have been no reports on the following: (1) whether co...

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Detalles Bibliográficos
Autores principales: Zhao, Zichen, Su, Chao, Xiu, Weigang, Wang, Weiya, Zeng, Shasha, Huang, Meijuan, Gong, Youling, Lu, You, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194866/
https://www.ncbi.nlm.nih.gov/pubmed/35711719
http://dx.doi.org/10.1016/j.jtocrr.2022.100343