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Brain-derived neurotrophic factor regulates LYN kinase–mediated myosin light chain kinase activation to modulate nonmuscle myosin II activity in hippocampal neurons

Myosins belong to a large superfamily of actin-dependent molecular motors. Nonmuscle myosin II (NM II) is involved in the morphology and function of neurons, but little is known about how NM II activity is regulated. Brain-derived neurotrophic factor (BDNF) is a prevalent neurotrophic factor in the...

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Detalles Bibliográficos
Autores principales: Li, Xiaobing, Yuan, Rong-Rong, Wang, Qixia, Chai, Shouyu, Zhang, Zhengying, Wang, Yue, Huang, Shu-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194867/
https://www.ncbi.nlm.nih.gov/pubmed/35598826
http://dx.doi.org/10.1016/j.jbc.2022.102054