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X chromosome inactivation in the human placenta is patchy and distinct from adult tissues

In humans, one of the X chromosomes in genetic females is inactivated by a process called X chromosome inactivation (XCI). Variation in XCI across the placenta may contribute to observed sex differences and variability in pregnancy outcomes. However, XCI has predominantly been studied in human adult...

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Detalles Bibliográficos
Autores principales: Phung, Tanya N., Olney, Kimberly C., Pinto, Brendan J., Silasi, Michelle, Perley, Lauren, O’Bryan, Jane, Kliman, Harvey J., Wilson, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194956/
https://www.ncbi.nlm.nih.gov/pubmed/35712697
http://dx.doi.org/10.1016/j.xhgg.2022.100121