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Mechanism of use-dependent Kv2 channel inhibition by RY785
Understanding the mechanism by which ion channel modulators act is critical for interpretation of their physiological effects and can provide insight into mechanisms of ion channel gating. The small molecule RY785 is a potent and selective inhibitor of Kv2 voltage-gated K(+) channels that has a use-...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195051/ https://www.ncbi.nlm.nih.gov/pubmed/35435946 http://dx.doi.org/10.1085/jgp.202112981 |