Validation of a Liquid Biopsy Protocol for Canine BRAFV595E Variant Detection in Dog Urine and Its Evaluation as a Diagnostic Test Complementary to Cytology

A significant proportion of canine urothelial carcinomas carry the driver valine to glutamic acid variation (V595E) in BRAF kinase. The detection of V595E may prove suitable to guide molecularly targeted therapies and support non-invasive diagnosis of the urogenital system by means of a liquid biops...

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Detalles Bibliográficos
Autores principales: Gentilini, Fabio, Palgrave, Christopher J., Neta, Michal, Tornago, Raimondo, Furlanello, Tommaso, McKay, Jennifer S., Sacchini, Federico, Turba, Maria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195143/
https://www.ncbi.nlm.nih.gov/pubmed/35711804
http://dx.doi.org/10.3389/fvets.2022.909934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195143/
https://www.ncbi.nlm.nih.gov/pubmed/35711804
http://dx.doi.org/10.3389/fvets.2022.909934

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