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Validation of a Liquid Biopsy Protocol for Canine BRAFV595E Variant Detection in Dog Urine and Its Evaluation as a Diagnostic Test Complementary to Cytology
A significant proportion of canine urothelial carcinomas carry the driver valine to glutamic acid variation (V595E) in BRAF kinase. The detection of V595E may prove suitable to guide molecularly targeted therapies and support non-invasive diagnosis of the urogenital system by means of a liquid biops...
Autores principales: | Gentilini, Fabio, Palgrave, Christopher J., Neta, Michal, Tornago, Raimondo, Furlanello, Tommaso, McKay, Jennifer S., Sacchini, Federico, Turba, Maria E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195143/ https://www.ncbi.nlm.nih.gov/pubmed/35711804 http://dx.doi.org/10.3389/fvets.2022.909934 |
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