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Biomimetic doxorubicin/ginsenoside co-loading nanosystem for chemoimmunotherapy of acute myeloid leukemia

BACKGROUND: Acute myeloid leukemia (AML) showed limited clinical therapeutic efficiency with chemotherapy for its multi-distributed lesions and hard-to-kill leukemia cells deep in the bone marrow. RESULTS: Here, a biomimetic nanosystem (DR@PLip) based on platelet membrane (PM) coating and doxorubici...

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Detalles Bibliográficos
Autores principales: Chen, Mo, Qiao, Yingyu, Cao, Jie, Ta, La, Ci, Tianyuan, Ke, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195256/
https://www.ncbi.nlm.nih.gov/pubmed/35701846
http://dx.doi.org/10.1186/s12951-022-01491-w