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Molecular Basis and Role of Siglec-7 Ligand Expression on Chronic Lymphocytic Leukemia B Cells

Siglec-7 (sialic acid–binding immunoglobulin-like lectin 7) is an immune checkpoint-like glycan recognition protein on natural killer (NK) cells. Cancer cells often upregulate Siglec ligands to subvert immunosurveillance, but the molecular basis of Siglec ligands has been elusive. In this study, we...

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Detalles Bibliográficos
Autores principales: Chang, Lan-Yi, Liang, Suh-Yuen, Lu, Shao-Chia, Tseng, Huan Chuan, Tsai, Ho-Yang, Tang, Chin-Ju, Sugata, Marcelia, Chen, Yi-Ju, Chen, Yu-Ju, Wu, Shang-Ju, Lin, Kuo-I, Khoo, Kay-Hooi, Angata, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195294/
https://www.ncbi.nlm.nih.gov/pubmed/35711441
http://dx.doi.org/10.3389/fimmu.2022.840388