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Mettl14-mediated m6A modification is essential for visual function and retinal photoreceptor survival

BACKGROUND: As the most abundant epigenetic modification of eukaryotic mRNA, N6-methyladenosine (m6A) modification has been shown to play a role in mammalian nervous system development and function by regulating mRNA synthesis and degeneration. However, the role of m6A modification in retinal photor...

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Detalles Bibliográficos
Autores principales: Yang, Yeming, Shuai, Ping, Li, Xiao, Sun, Kuanxiang, Jiang, Xiaoyan, Liu, Wenjing, Le, Weidong, Jiang, Haisong, Liu, Yuping, Zhu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195452/
https://www.ncbi.nlm.nih.gov/pubmed/35698136
http://dx.doi.org/10.1186/s12915-022-01335-x