Detection and Validation of Circular DNA Fragments Using Nanopore Sequencing

Occurrence of extra-chromosomal circular DNA is a phenomenon frequently observed in tumor cells, and the presence of such DNA has been recognized as a marker of adverse outcome across cancer types. We here describe a computational workflow for identification of DNA circles from long-read sequencing...

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Detalles Bibliográficos
Autores principales: Tüns, Alicia Isabell, Hartmann, Till, Magin, Simon, González, Rocío Chamorro, Henssen, Anton George, Rahmann, Sven, Schramm, Alexander, Köster, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195511/
https://www.ncbi.nlm.nih.gov/pubmed/35711922
http://dx.doi.org/10.3389/fgene.2022.867018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195511/
https://www.ncbi.nlm.nih.gov/pubmed/35711922
http://dx.doi.org/10.3389/fgene.2022.867018

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