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Detection and Validation of Circular DNA Fragments Using Nanopore Sequencing
Occurrence of extra-chromosomal circular DNA is a phenomenon frequently observed in tumor cells, and the presence of such DNA has been recognized as a marker of adverse outcome across cancer types. We here describe a computational workflow for identification of DNA circles from long-read sequencing...
Autores principales: | Tüns, Alicia Isabell, Hartmann, Till, Magin, Simon, González, Rocío Chamorro, Henssen, Anton George, Rahmann, Sven, Schramm, Alexander, Köster, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195511/ https://www.ncbi.nlm.nih.gov/pubmed/35711922 http://dx.doi.org/10.3389/fgene.2022.867018 |
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