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Breadth of Antibodies to Plasmodium falciparum Variant Surface Antigens Is Associated With Immunity in a Controlled Human Malaria Infection Study

BACKGROUND: Plasmodium falciparum variant surface antigens (VSAs) contribute to malaria pathogenesis by mediating cytoadhesion of infected red blood cells to the microvasculature endothelium. In this study, we investigated the association between anti-VSA antibodies and clinical outcome in a control...

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Detalles Bibliográficos
Autores principales: Kimingi, Hannah W., Kinyua, Ann W., Achieng, Nicole A., Wambui, Kennedy M., Mwangi, Shaban, Nguti, Roselyne, Kivisi, Cheryl A., Jensen, Anja T. R., Bejon, Philip, Kapulu, Melisa C., Abdi, Abdirahman I., Kinyanjui, Samson M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195513/
https://www.ncbi.nlm.nih.gov/pubmed/35711446
http://dx.doi.org/10.3389/fimmu.2022.894770