A Platelet-Rich Plasma-Derived Biologic Clears Staphylococcus aureus Biofilms While Mitigating Cartilage Degeneration and Joint Inflammation in a Clinically Relevant Large Animal Infectious Arthritis Model

The leading cause of treatment failure in Staphylococcus aureus infections is the development of biofilms. Biofilms are highly tolerant to conventional antibiotics which were developed against planktonic cells. Consequently, there is a lack of antibiofilm agents in the antibiotic development pipelin...

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Detalles Bibliográficos
Autores principales: Gilbertie, Jessica M., Schaer, Thomas P., Engiles, Julie B., Seiler, Gabriela S., Deddens, Bennett L., Schubert, Alicia G., Jacob, Megan E., Stefanovski, Darko, Ruthel, Gordon, Hickok, Noreen J., Stowe, Devorah M., Frink, Alexa, Schnabel, Lauren V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195519/
https://www.ncbi.nlm.nih.gov/pubmed/35711655
http://dx.doi.org/10.3389/fcimb.2022.895022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195519/
https://www.ncbi.nlm.nih.gov/pubmed/35711655
http://dx.doi.org/10.3389/fcimb.2022.895022

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