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Tuning the Properties of Protein-Based Polymers Using High-Performance Orthogonal Translation Systems for the Incorporation of Aromatic Non-Canonical Amino Acids
The incorporation of non-canonical amino acids (ncAAs) using engineered aminoacyl-tRNA synthetases (aaRSs) has emerged as a powerful methodology to expand the chemical repertoire of proteins. However, the low efficiencies of typical aaRS variants limit the incorporation of ncAAs to only one or a few...
Autores principales: | Gueta, Osher, Sheinenzon, Ortal, Azulay, Rotem, Shalit, Hadas, Strugach, Daniela S., Hadar, Dagan, Gelkop, Sigal, Milo, Anat, Amiram, Miriam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195583/ https://www.ncbi.nlm.nih.gov/pubmed/35711629 http://dx.doi.org/10.3389/fbioe.2022.913057 |
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