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JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKKβ

OBJECTIVE: Multiple myeloma (MM) remains incurable with high rates of relapse. New therapeutic drugs are therefore urgently needed to improve the prognosis. JaponiconeA (JA), a natural product isolated from Inula japonica Thunb, has shown good anti-MM potential. A comprehensive study should therefor...

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Detalles Bibliográficos
Autores principales: Zhang, Zilu, Ye, Chenjing, Liu, Jia, Xu, Wenbin, Wu, Chao, Yu, Qing, Xu, Xiaoguang, Zeng, Xinyi, Jin, Huizi, Wu, Yingli, Yan, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196056/
https://www.ncbi.nlm.nih.gov/pubmed/34570444
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0473