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Association of direct oral anticoagulant-proton pump inhibitor cotherapy with adverse outcomes: protocol for a population-based cohort study

INTRODUCTION: Proton pump inhibitors (PPIs) are widely used for primary and secondary prevention of upper gastrointestinal bleeding. However, there remains controversy about the overall net clinical benefit of PPIs (omeprazole, rabeprazole, pantoprazole, lansoprazole) when coprescribed with direct o...

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Detalles Bibliográficos
Autores principales: Wang, Mei, Paterson, Michael, Thabane, Lehana, Siegal, Deborah, Mbuagbaw, Lawrence, Targownik, Laura, Holbrook, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196177/
https://www.ncbi.nlm.nih.gov/pubmed/35697453
http://dx.doi.org/10.1136/bmjopen-2021-057991