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Deciphering Obesity-Related Gene Clusters Unearths SOCS3 Immune Infiltrates and 5mC/m6A Modifiers in Ossification of Ligamentum Flavum Pathogenesis

BACKGROUND: Ossification of ligamentum flavum (OLF) is an insidious and debilitating heterotopic ossifying disease with etiological heterogeneity and undefined pathogenesis. Obese individuals predispose to OLF, whereas the underlying connections between obesity phenotype and OLF pathomechanism are n...

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Detalles Bibliográficos
Autores principales: Zhang, Baoliang, Yuan, Lei, Chen, Guanghui, Chen, Xi, Yang, Xiaoxi, Fan, Tianqi, Sun, Chuiguo, Fan, Dongwei, Chen, Zhongqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196192/
https://www.ncbi.nlm.nih.gov/pubmed/35712246
http://dx.doi.org/10.3389/fendo.2022.861567