Layered Double Hydroxides-Loaded Sorafenib Inhibit Hepatic Stellate Cells Proliferation and Activation In Vitro and Reduce Fibrosis In Vivo

A core feature of liver fibrosis is the activation of hepatic stellate cells (HSCs), which are transformed into myofibroblasts and lead to the accumulation of extracellular matrix (ECM) proteins. In this study, we combined in vitro cellular efficacy with in vivo antifibrosis performance to evaluate...

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Detalles Bibliográficos
Autores principales: Peng, Wei, Zhang, Shiwen, Zhou, Wei, Zhao, Xinchen, Wang, Kexue, Yue, Chengxu, Wei, Xinyu, Pang, Siyan, Dong, Wei, Chen, Sulian, Chen, Changjie, Yang, Qingling, Wang, Wenrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196193/
https://www.ncbi.nlm.nih.gov/pubmed/35711641
http://dx.doi.org/10.3389/fbioe.2022.873971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196193/
https://www.ncbi.nlm.nih.gov/pubmed/35711641
http://dx.doi.org/10.3389/fbioe.2022.873971

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