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Receptor of Advanced Glycation End Products Deficiency Attenuates Cisplatin-Induced Acute Nephrotoxicity by Inhibiting Apoptosis, Inflammation and Restoring Fatty Acid Oxidation

Cisplatin is a widely used and potent anti-neoplastic agent, but severe and inescapable side effects in multiple normal tissues and organs limit its application, especially nephrotoxicity. Molecular mechanisms of cisplatin nephrotoxicity involve mitochondrial damage, oxidative stress, endoplasmic re...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Xi, Yuemei, Chen, Binyang, Zhao, Hairong, Yu, Wei, Xie, De, Liu, Weidong, He, Furong, Xu, Chenxi, Cheng, Jidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196246/
https://www.ncbi.nlm.nih.gov/pubmed/35712715
http://dx.doi.org/10.3389/fphar.2022.907133