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Tau Acts in Concert With Kinase/Phosphatase Underlying Synaptic Dysfunction

Alzheimer's disease (AD) is characterized by two pathological features: neurofibrillary tangles (NFTs), formed by microtubule-associated protein tau, and abnormal accumulation of amyloid-β (Aβ). Multiple evidence placed synaptic tau as the vital fact of AD pathology, especially at the very earl...

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Detalles Bibliográficos
Autores principales: Fan, Xing, Xia, Liye, Zhou, Zheng, Qiu, Yanyan, Zhao, Chenhao, Yin, Xiaomin, Qian, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196307/
https://www.ncbi.nlm.nih.gov/pubmed/35711910
http://dx.doi.org/10.3389/fnagi.2022.908881