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Cancer testis antigens and genomic instability: More than immunology(,)

Cancer testis antigens or genes (CTA, CTG) are predominantly expressed in adult testes while silenced in most or all somatic tissues with sporadic expression in many human cancers. Concerted misexpression of numerous CTA/CTGs is rarely observed. This finding argues against the germ cell theory of ca...

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Detalles Bibliográficos
Autores principales: Jay, Ash, Reitz, Diedre, Namekawa, Satoshi H., Heyer, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196322/
https://www.ncbi.nlm.nih.gov/pubmed/34481156
http://dx.doi.org/10.1016/j.dnarep.2021.103214