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Loss of MAPK8IP3 Affects Endocytosis in Neurons

Perturbations in endo-lysosomal trafficking pathways are linked to many neurodevelopmental and neurodegenerative diseases. Of relevance to our current study, MAPK8IP3/JIP3, a brain enriched putative adaptor between lysosomes and motors has been previously implicated as a key regulator of axonal lyso...

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Detalles Bibliográficos
Autores principales: Snead, Amanda M., Gowrishankar, Swetha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196590/
https://www.ncbi.nlm.nih.gov/pubmed/35711470
http://dx.doi.org/10.3389/fncel.2022.828071