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DYNC1LI2 regulates localization of the chaperone-mediated autophagy receptor LAMP2A and improves cellular homeostasis in cystinosis

The dynein motor protein complex is required for retrograde transport but the functions of the intermediate-light chains that form the cargo-binding complex are not elucidated and the importance of individual subunits in maintaining cellular homeostasis is unknown. Here, using mRNA arrays and protei...

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Detalles Bibliográficos
Autores principales: Rahman, Farhana, Johnson, Jennifer L., Zhang, Jinzhong, He, Jing, Pestonjamasp, Kersi, Cherqui, Stephanie, Catz, Sergio D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196850/
https://www.ncbi.nlm.nih.gov/pubmed/34643468
http://dx.doi.org/10.1080/15548627.2021.1971937