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Pulmonary drug delivery and retention: A computational study to identify plausible parameters based on a coupled airway-mucus flow model
Pulmonary drug delivery systems rely on inhalation of drug-laden aerosols produced from aerosol generators such as inhalers, nebulizers etc. On deposition, the drug molecules diffuse in the mucus layer and are also subjected to mucociliary advection which transports the drugs away from the initial d...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197018/ https://www.ncbi.nlm.nih.gov/pubmed/35653381 http://dx.doi.org/10.1371/journal.pcbi.1010143 |