Daf-16 mediated repression of cytosolic ribosomal protein genes facilitates a hypoxia sensitive to hypoxia resistant transformation in long-lived germline mutants

In C. elegans, germline ablation leads to long life span and stress resistance. It has been reported that mutations that block oogenesis or an upstream step in germline development confer strong resistance to hypoxia. We demonstrate here that the hypoxia resistance of sterile mutants is dependent on...

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Detalles Bibliográficos
Autores principales: Hemphill, Cassidy, Pylarinou-Sinclair, Evye, Itani, Omar, Scott, Barbara, Crowder, C. Michael, Van Gilst, Marc Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197040/
https://www.ncbi.nlm.nih.gov/pubmed/35622856
http://dx.doi.org/10.1371/journal.pgen.1009672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197040/
https://www.ncbi.nlm.nih.gov/pubmed/35622856
http://dx.doi.org/10.1371/journal.pgen.1009672

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