Testing non-autonomous antimalarial gene drive effectors using self-eliminating drivers in the African mosquito vector Anopheles gambiae

Gene drives for mosquito population modification are novel tools for malaria control. Strategies to safely test antimalarial effectors in the field are required. Here, we modified the Anopheles gambiae zpg locus to host a CRISPR/Cas9 integral gene drive allele (zpg(D)) and characterized its behaviou...

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Detalles Bibliográficos
Autores principales: Ellis, David A., Avraam, George, Hoermann, Astrid, Wyer, Claudia A. S., Ong, Yi Xin, Christophides, George K., Windbichler, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197043/
https://www.ncbi.nlm.nih.gov/pubmed/35653396
http://dx.doi.org/10.1371/journal.pgen.1010244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197043/
https://www.ncbi.nlm.nih.gov/pubmed/35653396
http://dx.doi.org/10.1371/journal.pgen.1010244

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