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Role of water-bridged interactions in metal ion coupled protein allostery

Allosteric communication between distant parts of proteins controls many cellular functions, in which metal ions are widely utilized as effectors to trigger the allosteric cascade. Due to the involvement of strong coordination interactions, the energy landscape dictating the metal ion binding is int...

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Detalles Bibliográficos
Autores principales: Guan, Xingyue, Tan, Cheng, Li, Wenfei, Wang, Wei, Thirumalai, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197054/
https://www.ncbi.nlm.nih.gov/pubmed/35653400
http://dx.doi.org/10.1371/journal.pcbi.1010195