sumSTAAR: A flexible framework for gene-based association studies using GWAS summary statistics

Gene-based association analysis is an effective gene-mapping tool. Many gene-based methods have been proposed recently. However, their power depends on the underlying genetic architecture, which is rarely known in complex traits, and so it is likely that a combination of such methods could serve as...

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Detalles Bibliográficos
Autores principales: Belonogova, Nadezhda M., Svishcheva, Gulnara R., Kirichenko, Anatoly V., Zorkoltseva, Irina V., Tsepilov, Yakov A., Axenovich, Tatiana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197066/
https://www.ncbi.nlm.nih.gov/pubmed/35653402
http://dx.doi.org/10.1371/journal.pcbi.1010172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197066/
https://www.ncbi.nlm.nih.gov/pubmed/35653402
http://dx.doi.org/10.1371/journal.pcbi.1010172

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