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Fructose Induces Pulmonary Fibrotic Phenotype Through Promoting Epithelial-Mesenchymal Transition Mediated by ROS-Activated Latent TGF-β1

Fructose is a commonly used food additive and has many adverse effects on human health, but it is unclear whether fructose impacts pulmonary fibrosis. TGF-β1, a potent fibrotic inducer, is produced as latent complexes by various cells, including alveolar epithelial cells, macrophages, and fibroblast...

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Detalles Bibliográficos
Autores principales: Xu, Xiaoxiao, Ma, Chuang, Wu, Hang, Ma, Yuanqiao, Liu, Zejin, Zhong, Peijie, Jin, Chaolei, Ning, Wenjuan, Wu, Xiao, Zhang, Yijie, Han, Jichang, Wang, Junpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197188/
https://www.ncbi.nlm.nih.gov/pubmed/35711535
http://dx.doi.org/10.3389/fnut.2022.850689