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Fructose Induces Pulmonary Fibrotic Phenotype Through Promoting Epithelial-Mesenchymal Transition Mediated by ROS-Activated Latent TGF-β1
Fructose is a commonly used food additive and has many adverse effects on human health, but it is unclear whether fructose impacts pulmonary fibrosis. TGF-β1, a potent fibrotic inducer, is produced as latent complexes by various cells, including alveolar epithelial cells, macrophages, and fibroblast...
Autores principales: | Xu, Xiaoxiao, Ma, Chuang, Wu, Hang, Ma, Yuanqiao, Liu, Zejin, Zhong, Peijie, Jin, Chaolei, Ning, Wenjuan, Wu, Xiao, Zhang, Yijie, Han, Jichang, Wang, Junpeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197188/ https://www.ncbi.nlm.nih.gov/pubmed/35711535 http://dx.doi.org/10.3389/fnut.2022.850689 |
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