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Mechanical Strain Induces Transcriptomic Reprogramming of Saphenous Vein Progenitors

Intimal hyperplasia is the leading cause of graft failure in aortocoronary bypass grafts performed using human saphenous vein (SV). The long-term consequences of the altered pulsatile stress on the cells that populate the vein wall remains elusive, particularly the effects on saphenous vein progenit...

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Detalles Bibliográficos
Autores principales: Maselli, Davide, Garoffolo, Gloria, Cassanmagnago, Giada Andrea, Vono, Rosa, Ruiter, Matthijs S., Thomas, Anita C., Madeddu, Paolo, Pesce, Maurizio, Spinetti, Gaia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197233/
https://www.ncbi.nlm.nih.gov/pubmed/35711359
http://dx.doi.org/10.3389/fcvm.2022.884031