Design of a Bispecific HIV Entry Inhibitor Targeting the Cell Receptor CD4 and Viral Fusion Protein Gp41

Given the high variability and drug-resistance problem by human immunodeficiency virus type 1 (HIV-1), the development of bispecific or multi-specific inhibitors targeting different steps of HIV entry is highly appreciated. We previously generated a very potent short-peptide–based HIV fusion inhibit...

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Detalles Bibliográficos
Autores principales: Yan, Hongxia, Wu, Tong, Chen, Yue, Jin, Hongliang, Li, Li, Zhu, Yuanmei, Chong, Huihui, He, Yuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197378/
https://www.ncbi.nlm.nih.gov/pubmed/35711654
http://dx.doi.org/10.3389/fcimb.2022.916487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197378/
https://www.ncbi.nlm.nih.gov/pubmed/35711654
http://dx.doi.org/10.3389/fcimb.2022.916487

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