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Design of a Bispecific HIV Entry Inhibitor Targeting the Cell Receptor CD4 and Viral Fusion Protein Gp41
Given the high variability and drug-resistance problem by human immunodeficiency virus type 1 (HIV-1), the development of bispecific or multi-specific inhibitors targeting different steps of HIV entry is highly appreciated. We previously generated a very potent short-peptide–based HIV fusion inhibit...
Autores principales: | Yan, Hongxia, Wu, Tong, Chen, Yue, Jin, Hongliang, Li, Li, Zhu, Yuanmei, Chong, Huihui, He, Yuxian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197378/ https://www.ncbi.nlm.nih.gov/pubmed/35711654 http://dx.doi.org/10.3389/fcimb.2022.916487 |
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