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DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells

In a previous study, it was reported that Yap1 and Wwtr1 in zebrafish regulates the morphogenesis of the posterior body and epidermal fin fold (Kimelman et al., 2017). We report here that DNA damage induces apoptosis of epidermal basal cells (EBCs) in zebrafish yap1(-/-);wwtr1(-/-) embryos. Specific...

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Detalles Bibliográficos
Autores principales: Lai, Jason KH, Toh, Pearlyn JY, Cognart, Hamizah A, Chouhan, Geetika, Saunders, Timothy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197390/
https://www.ncbi.nlm.nih.gov/pubmed/35635436
http://dx.doi.org/10.7554/eLife.72302