Chondroitin sulfate proteoglycan 4,6 sulfation regulates sympathetic nerve regeneration after myocardial infarction

Sympathetic denervation of the heart following ischemia/reperfusion induced myocardial infarction (MI) is sustained by chondroitin sulfate proteoglycans (CSPGs) in the cardiac scar. Denervation predicts risk of sudden cardiac death in humans. Blocking CSPG signaling restores sympathetic axon outgrow...

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Detalles Bibliográficos
Autores principales: Blake, Matthew R, Parrish, Diana C, Staffenson, Melanie A, Sueda, Shanice, Woodward, William R, Habecker, Beth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197393/
https://www.ncbi.nlm.nih.gov/pubmed/35604022
http://dx.doi.org/10.7554/eLife.78387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197393/
https://www.ncbi.nlm.nih.gov/pubmed/35604022
http://dx.doi.org/10.7554/eLife.78387

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