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Reducing ER stress with chaperone therapy reverses sleep fragmentation and cognitive decline in aged mice
As the aging population grows, the need to understand age‐related changes in health is vital. Two prominent behavioral changes that occur with age are disrupted sleep and impaired cognition. Sleep disruptions lead to perturbations in proteostasis and endoplasmic reticulum (ER) stress in mice. Furthe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197403/ https://www.ncbi.nlm.nih.gov/pubmed/35488730 http://dx.doi.org/10.1111/acel.13598 |