Cargando…

Chaperone‐mediated autophagy degrades Keap1 and promotes Nrf2‐mediated antioxidative response

Accumulation of oxidative stress is highly intertwined with aging process and contributes to aging‐related diseases, such as neurodegenerative diseases. Deciphering the molecular machinery that regulates oxidative stress is fundamental to further uncovering the pathogenesis of these diseases. Chaper...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Lin, He, Shulei, Huang, Lu, Ren, Dongni, Nie, Tiejian, Tao, Kai, Xia, Li, Lu, Fangfang, Mao, Zixu, Yang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197408/
https://www.ncbi.nlm.nih.gov/pubmed/35535673
http://dx.doi.org/10.1111/acel.13616