TNF‐α/IFN‐γ synergy amplifies senescence‐associated inflammation and SARS‐CoV‐2 receptor expression via hyper‐activated JAK/STAT1

Older age and underlying conditions such as diabetes/obesity or immunosuppression are leading host risk factors for developing severe complications from COVID‐19 infection. The pathogenesis of COVID‐19‐related cytokine storm, tissue damage, and fibrosis may be interconnected with fundamental aging p...

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Detalles Bibliográficos
Autores principales: Kandhaya‐Pillai, Renuka, Yang, Xiaomeng, Tchkonia, Tamar, Martin, George M., Kirkland, James L., Oshima, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197409/
https://www.ncbi.nlm.nih.gov/pubmed/35645319
http://dx.doi.org/10.1111/acel.13646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197409/
https://www.ncbi.nlm.nih.gov/pubmed/35645319
http://dx.doi.org/10.1111/acel.13646

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