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TNF‐α/IFN‐γ synergy amplifies senescence‐associated inflammation and SARS‐CoV‐2 receptor expression via hyper‐activated JAK/STAT1
Older age and underlying conditions such as diabetes/obesity or immunosuppression are leading host risk factors for developing severe complications from COVID‐19 infection. The pathogenesis of COVID‐19‐related cytokine storm, tissue damage, and fibrosis may be interconnected with fundamental aging p...
Autores principales: | Kandhaya‐Pillai, Renuka, Yang, Xiaomeng, Tchkonia, Tamar, Martin, George M., Kirkland, James L., Oshima, Junko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197409/ https://www.ncbi.nlm.nih.gov/pubmed/35645319 http://dx.doi.org/10.1111/acel.13646 |
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