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Graft-versus-host disease: establishing IL-33 as an important costimulatory molecule
Approximately half of patients with hematologic malignancy who are treated with allogeneic hematopoietic stem cell transplantation (alloHCT) experience graft-versus-host disease (GVHD), which has high mortality rates despite immunosuppressive therapy. IL-12 is known to drive donor T cells toward an...
Autores principales: | Ferrara, James, Prado-Acosta, Mariano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197507/ https://www.ncbi.nlm.nih.gov/pubmed/35703182 http://dx.doi.org/10.1172/JCI160692 |
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