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Favorable vaccine-induced SARS-CoV-2–specific T cell response profile in patients undergoing immune-modifying therapies

BACKGROUND: Patients undergoing immune-modifying therapies demonstrate a reduced humoral response after COVID-19 vaccination, but we lack a proper evaluation of the effect of such therapies on vaccine-induced T cell responses. METHODS: We longitudinally characterized humoral and spike-specific T cel...

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Detalles Bibliográficos
Autores principales: Qui, Martin, Le Bert, Nina, Chan, Webber Pak Wo, Tan, Malcolm, Hang, Shou Kit, Hariharaputran, Smrithi, Sim, Jean Xiang Ying, Low, Jenny Guek Hong, Ng, Weiling, Wan, Wei Yee, Ang, Tiing Leong, Bertoletti, Antonio, Salazar, Ennaliza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197512/
https://www.ncbi.nlm.nih.gov/pubmed/35536644
http://dx.doi.org/10.1172/JCI159500