PD-1 and ICOS coexpression identifies tumor-reactive CD4(+) T cells in human solid tumors

CD4(+) Th cells play a key role in orchestrating immune responses, but the identity of the CD4(+) Th cells involved in the antitumor immune response remains to be defined. We analyzed the immune cell infiltrates of head and neck squamous cell carcinoma and colorectal cancers and identified a subset...

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Detalles Bibliográficos
Autores principales: Duhen, Rebekka, Fesneau, Olivier, Samson, Kimberly A., Frye, Alexandra K., Beymer, Michael, Rajamanickam, Venkatesh, Ross, David, Tran, Eric, Bernard, Brady, Weinberg, Andrew D., Duhen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197519/
https://www.ncbi.nlm.nih.gov/pubmed/35439168
http://dx.doi.org/10.1172/JCI156821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197519/
https://www.ncbi.nlm.nih.gov/pubmed/35439168
http://dx.doi.org/10.1172/JCI156821

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