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PD-1 and ICOS coexpression identifies tumor-reactive CD4(+) T cells in human solid tumors
CD4(+) Th cells play a key role in orchestrating immune responses, but the identity of the CD4(+) Th cells involved in the antitumor immune response remains to be defined. We analyzed the immune cell infiltrates of head and neck squamous cell carcinoma and colorectal cancers and identified a subset...
Autores principales: | Duhen, Rebekka, Fesneau, Olivier, Samson, Kimberly A., Frye, Alexandra K., Beymer, Michael, Rajamanickam, Venkatesh, Ross, David, Tran, Eric, Bernard, Brady, Weinberg, Andrew D., Duhen, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197519/ https://www.ncbi.nlm.nih.gov/pubmed/35439168 http://dx.doi.org/10.1172/JCI156821 |
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