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Siglec-F–expressing neutrophils are essential for creating a profibrotic microenvironment in renal fibrosis

The roles of neutrophils in renal inflammation are currently unclear. On examining these cells in the unilateral ureteral obstruction murine model of chronic kidney disease, we found that the injured kidney bore a large and rapidly expanding population of neutrophils that expressed the eosinophil ma...

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Detalles Bibliográficos
Autores principales: Ryu, Seungwon, Shin, Jae Woo, Kwon, Soie, Lee, Jiwon, Kim, Yong Chul, Bae, Yoe-Sik, Bae, Yong-Soo, Kim, Dong Ki, Kim, Yon Su, Yang, Seung Hee, Kim, Hye Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197522/
https://www.ncbi.nlm.nih.gov/pubmed/35482420
http://dx.doi.org/10.1172/JCI156876