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CDK4/6 Inhibitors in Combination Therapies: Better in Company Than Alone: A Mini Review

The cyclin D-CDK4/6 complexes play a pivotal role in controlling the cell cycle. Deregulation in cyclin D-CDK4/6 pathway has been described in many types of cancer and it invariably leads to uncontrolled cell proliferation. Many efforts have been made to develop a target therapy able to inhibit CDK4...

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Detalles Bibliográficos
Autores principales: Rampioni Vinciguerra, Gian Luca, Sonego, Maura, Segatto, Ilenia, Dall’Acqua, Alessandra, Vecchione, Andrea, Baldassarre, Gustavo, Belletti, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197541/
https://www.ncbi.nlm.nih.gov/pubmed/35712501
http://dx.doi.org/10.3389/fonc.2022.891580