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Aerobic Exercise Inhibited P2X7 Purinergic Receptors to Improve Cardiac Remodeling in Mice With Type 2 Diabetes

Background: Diabetic cardiomyopathy (DCM), the main complication of diabetes mellitus, presents as cardiac dysfunction by ventricular remodeling. In addition, the inhibition of P2X7 purinergic receptors (P2X7R) alleviates cardiac fibrosis and apoptosis in Type 1 diabetes. However, whether exercise t...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Li, Jianmin, Li, Hui, Zhong, Xin, Wang, Luya, Zhao, Shujue, Liu, Xuesheng, Huang, Zhouqing, Wang, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197582/
https://www.ncbi.nlm.nih.gov/pubmed/35711309
http://dx.doi.org/10.3389/fphys.2022.828020