Mendelian imputation of parental genotypes improves estimates of direct genetic effects

Effects estimated by genome-wide association studies (GWASs) include effects of alleles in an individual on that individual (direct genetic effects), indirect genetic effects (for example, effects of alleles in parents on offspring through the environment) and bias from confounding. Within-family ge...

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Detalles Bibliográficos
Autores principales: Young, Alexander I., Nehzati, Seyed Moeen, Benonisdottir, Stefania, Okbay, Aysu, Jayashankar, Hariharan, Lee, Chanwook, Cesarini, David, Benjamin, Daniel J., Turley, Patrick, Kong, Augustine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197765/
https://www.ncbi.nlm.nih.gov/pubmed/35681053
http://dx.doi.org/10.1038/s41588-022-01085-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197765/
https://www.ncbi.nlm.nih.gov/pubmed/35681053
http://dx.doi.org/10.1038/s41588-022-01085-0

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