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Mendelian imputation of parental genotypes improves estimates of direct genetic effects
Effects estimated by genome-wide association studies (GWASs) include effects of alleles in an individual on that individual (direct genetic effects), indirect genetic effects (for example, effects of alleles in parents on offspring through the environment) and bias from confounding. Within-family ge...
Autores principales: | Young, Alexander I., Nehzati, Seyed Moeen, Benonisdottir, Stefania, Okbay, Aysu, Jayashankar, Hariharan, Lee, Chanwook, Cesarini, David, Benjamin, Daniel J., Turley, Patrick, Kong, Augustine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197765/ https://www.ncbi.nlm.nih.gov/pubmed/35681053 http://dx.doi.org/10.1038/s41588-022-01085-0 |
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