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De Novo design of potential inhibitors against SARS-CoV-2 Mpro

The impact of the ravages of COVID-19 on people's lives is obvious, and the development of novel potential inhibitors against SARS-CoV-2 main protease (Mpro), which has been validated as a potential target for drug design, is urgently needed. This study developed a model named MproI-GEN, which...

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Detalles Bibliográficos
Autores principales: Li, Shimeng, Wang, Lianxin, Meng, Jinhui, Zhao, Qi, Zhang, Li, Liu, Hongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197785/
https://www.ncbi.nlm.nih.gov/pubmed/35763931
http://dx.doi.org/10.1016/j.compbiomed.2022.105728